eritropoietina

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ormone

Risorse esterne

identificativo Freebase
/m/01fwr3[1]
identificativo della Biblioteca del Congresso
sh85044756[2]

soggetto indicato come: Erythropoietin

identificativo RefSeq di una proteina
NP_000790[3]
Ensembl protein ID
ENSP00000252723[4]
identificativo Gran Enciclopèdia Catalana
eritropoetina
identificativo UniProt
P01588[5]
identificativo Gran Enciclopèdia Catalana (obsoleto)
0103932
identificativo Den Store Danske
epo
erythropoietin
identificativo UNII
64FS3BFH5W
identificativo NDL
00577035
identificativo WikiSkripta
15467
identificativo UK Parliament Thesaurus
9984

soggetto indicato come: Erythropoietin

identificativo Microsoft Academic
2778534260
identificativo PDB
1BUY[6]
1CN4[6]
1EER[6]
identificativo Thesaurus BNCF
73525
identificativo WorldNet 3.1 di un synset
14874504-n[7]
identificativo GND
4152964-9
identificativo NALT
28017
Great Russian Encyclopedia portal ID
eritropoetin-ea05f9
identificativo OpenAlex
C2778534260[8]
identificativo J9U della Biblioteca nazionale israeliana
987007553190405171[9]

sottoclasse di

proteina[5]

parte 'e

erythropoietin[10]
four-helical cytokine-like, core[10]
Erythropoietin/thrombopoeitin, conserved site, protein family[11]

trovato nella tassonomia de

Homo sapiens[5]

codificato da

eritropoietina[5]

funzione molecolare

funzione ormonale[12][13]

metodo di determinazione: IEA

protein kinase activator activity[14]

metodo di determinazione: IEA

legame dei farmaci alle proteine plasmatiche[15][16][17]

metodo di determinazione: IPI

erythropoietin receptor binding[18][19]

metodo di determinazione: IEA, IMP

cytokine activity[20]

metodo di determinazione: IDA

cytokine activity[21][22]

metodo di determinazione: IBA, IDA

erythropoietin receptor binding[23][13][22]

metodo di determinazione: IBA, IEA, IMP

protein kinase activator activity[24][22]

metodo di determinazione: IBA, IEA

componente cellulare

regione extracellulare[25][12][13]

metodo di determinazione: IEA, TAS

cell surface[26]

metodo di determinazione: IDA

cell body[24]

metodo di determinazione: IEA

spazio extracellulare[14][27]

metodo di determinazione: IDA, IEA

spazio extracellulare[24][26][22]

metodo di determinazione: IBA, IDA, IEA

processo biologico

erythrocyte maturation[12]

metodo di determinazione: IEA

negative regulation of cation channel activity[26]

metodo di determinazione: IDA

response to interleukin-1[24]

metodo di determinazione: IEA

response to hypoxia[14]

metodo di determinazione: IEA

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress[26]

metodo di determinazione: IDA

response to nutrient[24]

metodo di determinazione: IEA

response to salt stress[24]

metodo di determinazione: IEA

negative regulation of erythrocyte apoptotic process[26]

metodo di determinazione: IDA

response to testosterone[24]

metodo di determinazione: IEA

regulation of transcription by RNA polymerase II[24]

metodo di determinazione: IEA

response to hyperoxia[24]

metodo di determinazione: IEA

positive regulation of Ras protein signal transduction[28]

metodo di determinazione: IDA

invecchiamento[24]

metodo di determinazione: IEA

negative regulation of apoptotic process[24]

metodo di determinazione: IEA

negative regulation of transcription by RNA polymerase II[29]

metodo di determinazione: IMP

response to electrical stimulus[24]

metodo di determinazione: IEA

circolazione del sangue[30]

metodo di determinazione: NAS

response to estrogen[24]

metodo di determinazione: IEA

cellular hyperosmotic response[26]

metodo di determinazione: IDA

positive regulation of transcription, DNA-templated[31]

metodo di determinazione: IDA

response to vitamin A[24]

metodo di determinazione: IEA

response to lipopolysaccharide[24]

metodo di determinazione: IEA

acute-phase response[24]

metodo di determinazione: IEA

peptidyl-serine phosphorylation[24]

metodo di determinazione: IEA

response to axon injury[24]

metodo di determinazione: IEA

hemoglobin biosynthetic process[14]

metodo di determinazione: IEA

positive regulation of neuron differentiation[24]

metodo di determinazione: IEA

positive regulation of cell population proliferation[14][28]

metodo di determinazione: IDA, IEA

regulation of transcription from RNA polymerase II promoter in response to hypoxia[25]

metodo di determinazione: TAS

positive regulation of ERK1 and ERK2 cascade[24]

metodo di determinazione: IEA

positive regulation of neuron projection development[24]

metodo di determinazione: IEA

negative regulation of calcium ion transport into cytosol[26]

metodo di determinazione: IDA

negative regulation of myeloid cell apoptotic process[24]

metodo di determinazione: IEA

activation of protein kinase activity[32]

metodo di determinazione: IEA

embryo implantation[24]

metodo di determinazione: IEA

trasduzione del segnale[30]

metodo di determinazione: NAS

positive regulation of activated T cell proliferation[24]

metodo di determinazione: IEA

positive regulation of protein kinase activity[24]

metodo di determinazione: IEA

negative regulation of neuron death[24]

metodo di determinazione: IEA

apoptosi[24]

metodo di determinazione: IEA

response to dexamethasone[24]

metodo di determinazione: IEA

proliferazione cellulare[23]

metodo di determinazione: IMP

erythrocyte differentiation[23][24][33]

metodo di determinazione: IDA, IEA, IMP

erythropoietin-mediated signaling pathway[18]

metodo di determinazione: IMP

positive regulation of tyrosine phosphorylation of STAT protein[31]

metodo di determinazione: IDA

regulation of signaling receptor activity[32]

metodo di determinazione: IEA

response to hypoxia[24][22]

metodo di determinazione: IBA, IEA

positive regulation of cell population proliferation[24][31][22]

metodo di determinazione: IBA, IDA, IEA

erythropoietin-mediated signaling pathway[23][22]

metodo di determinazione: IBA, IMP

hemoglobin biosynthetic process[24][22]

metodo di determinazione: IBA, IEA

positive regulation of Ras protein signal transduction[34][35]

metodo di determinazione: IBA, IDA

positive regulation of phosphatidylinositol 3-kinase signaling[25]

metodo di determinazione: TAS

positive regulation of Ras protein signal transduction[25][31][22]

metodo di determinazione: IBA, IDA, TAS

status giuridico medicina

boxed warning[36]

immagine Gene Atlas

corrisponde esattamente

http://purl.uniprot.org/uniprot/P01588[37]

è fatte 'e

azoto
carbonio
Erythropoietin/thrombopoeitin, conserved site[10]

categoria su Commons

Erythropoietin

Riferimento

  1. ↑ Freebase Data Dumps, 28 ott 2013
  2. ↑ Gemeinsame Normdatei
  3. ↑ NCBI Gene, 30 Maj 2020, 2056
  4. ↑ Ensembl Release 99, ENSP00000252723
  5. ↑ 5,0 5,1 5,2 5,3 UniProt, 13 Nuv 2019, P01588
  6. ↑ 6,0 6,1 6,2 P01588, 4 Aùs 2016, UniProt, Lengua ngrese
  7. ↑ GF WordNet
  8. ↑ OpenAlex, 26 Jen 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  9. ↑ Biblioteca nazionale di Israele
  10. ↑ 10,0 10,1 10,2 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P01588
  11. ↑ inferred from protein domain or family
  12. ↑ 12,0 12,1 12,2 IEA, 8 Abb 2019, P01588, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, UniProt
  13. ↑ 13,0 13,1 13,2 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, InterPro, GOA
  14. ↑ 14,0 14,1 14,2 14,3 14,4 IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 27 Màr 2018, Ensembl, GOA
  15. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, IntAct protein interaction database, Erythropoietin Stimulates Tumor Growth via EphB4., GOA
  16. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, IntAct protein interaction database, Efficiency of signalling through cytokine receptors depends critically on receptor orientation, GOA
  17. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, IntAct protein interaction database, LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells, GOA
  18. ↑ 18,0 18,1 IMP, 27 Màr 2018, P01588, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, UniProt
  19. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 27 Màr 2018, InterPro, GOA
  20. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 27 Màr 2018, British Heart Foundation, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA
  21. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, British Heart Foundation, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA
  22. ↑ 22,0 22,1 22,2 22,3 22,4 22,5 22,6 22,7 22,8 IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  23. ↑ 23,0 23,1 23,2 23,3 IMP, 8 Abb 2019, P01588, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, UniProt
  24. ↑ 24,00 24,01 24,02 24,03 24,04 24,05 24,06 24,07 24,08 24,09 24,10 24,11 24,12 24,13 24,14 24,15 24,16 24,17 24,18 24,19 24,20 24,21 24,22 24,23 24,24 24,25 24,26 24,27 24,28 24,29 24,30 24,31 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, Ensembl, GOA
  25. ↑ 25,0 25,1 25,2 25,3 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, Reactome, GOA
  26. ↑ 26,0 26,1 26,2 26,3 26,4 26,5 26,6 IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, British Heart Foundation, Inhibition of Erythrocyte Cation Channels by Erythropoietin, GOA
  27. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 27 Màr 2018, British Heart Foundation, Inhibition of Erythrocyte Cation Channels by Erythropoietin, GOA
  28. ↑ 28,0 28,1 IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 27 Màr 2018, British Heart Foundation, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA
  29. ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, British Heart Foundation, Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis, GOA
  30. ↑ 30,0 30,1 NAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, Proteome Inc., Isolation and characterization of genomic and cDNA clones of human erythropoietin, GOA
  31. ↑ 31,0 31,1 31,2 31,3 IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, British Heart Foundation, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA
  32. ↑ 32,0 32,1 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, Gene Ontology Consortium, GOA
  33. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, 8 Abb 2019, British Heart Foundation, Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice, GOA
  34. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 10 set 2018, British Heart Foundation, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA
  35. ↑ IBA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, 10 set 2018, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  36. ↑ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  37. ↑ registro identifiers.org
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