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Benazepril

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farmaco antipertensivo

Risorse esterne

MedlinePlus drug identifier
a692011
numero CAS
86541-75-5[1][2]
numero Beilstein
4302258[3]
identificativo PubChem
5362124[4][5]
40466887[5]
identificativo MeSH
C044946[6]
LiverTox ID
Benazepril
identificativo KEGG
C06843[3]
D07499[3]
identificativo ChEMBL
CHEMBL838[7]
InChIKey
XPCFTKFZXHTYIP-PMACEKPBSA-N[4][8]
identificativo UNII
UDM7Q7QWP8[1][5]
identificativo Drugbank
DB00542[5]
identificativo HMDB
HMDB0014682[9][5]
identificativo ChEBI
3011[7][10]

tipo di relazione: corrispondenza esatta

identificativo DSSTOX sostanza
DTXSID5022645[11][5]
codice ATC
C09AA07[12]
UMLS CUI
C0053091[1]
identificativo IUPHAR
6374[13]
SureChEMBL ID
SCHEMBL16396[9][5]
identificativo Denominazione Comune Internazionale dell'OMS
6129[14]
identificativo OpenAlex
C2777363265[15]
identificativo Freebase
/m/06z2t5[16]
identificativo DSSTOX di un composto chimico
DTXCID602645
identificativo Microsoft Academic
2777363265
InChI
InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1[4]
identificativo ChemSpider
4514935[17]
identificativo NDF-RT
N0000148336[1]
DrugCentral ID
299[18]
WikiProjectMed ID
Benazepril
RxNorm CUI
18867[1]
Probes And Drugs ID
PD010141
identificativo HSDB
7081[19]

no tipo 'e

type of chemical entity

sottoclasse di

2-[3-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid[9]

è ausato comme

farmaco

struttura chimica

modello molecolare

raffigura: modello ad asta e sfera

massa

424,199822 unità e' massa atomeca[20]

stereoisomero di

CGP-42456A[21]
CGP-42454a[21]

formula chimica

C₂₄H₂₈N₂O₅[4]

SMILES canonico

CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O[4]

SMILES isomerico

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O[4]

dose giornaliera definita

7,5 milligrammo[22]

via di somministrazione: per os

principio attivo in

Lotensin[23]

Denominazione Comune Internazionale

benazepril[3][24]

condizione medica trattata

insufficienza cardiaca congestizia[25]
ipertensione[25][26]

LiverTox likelihood score

LiverTox toxicity likelihood category D[27]

ruolo del soggetto

ACE-inibitore[28][29]
farmaco antipertensivo[29]

raffigurazione schematica

categoria su Commons

Benazepril

Riferimento

  1. ↑ 1,0 1,1 1,2 1,3 1,4 Global Substance Registration System, 19 Nuv 2016, Lengua ngrese, benazepril, UDM7Q7QWP8
  2. ↑ CAS Common Chemistry, 9 Abb 2021, https://commonchemistry.cas.org/detail?cas_rn=86541-75-5, XPCFTKFZXHTYIP-PMACEKPBSA-N
  3. ↑ 3,0 3,1 3,2 3,3 ChEBI, 3 ott 2016, Lengua ngrese, benazepril, 3011
  4. ↑ 4,0 4,1 4,2 4,3 4,4 4,5 PubChem, 19 Nuv 2016, Lengua ngrese, 5362124, benazepril
  5. ↑ 5,0 5,1 5,2 5,3 5,4 5,5 5,6 XPCFTKFZXHTYIP-PMACEKPBSA-N, InChIKey
  6. ↑ Medical Subject Headings, 14 Màr 2018, C044946
  7. ↑ 7,0 7,1 ChEMBL, 19 Nuv 2016, Lengua ngrese, BENAZEPRIL, CHEMBL838
  8. ↑ ChEBI release 2020-09-01
  9. ↑ 9,0 9,1 9,2 inferred from InChIKey
  10. ↑ InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1, International Chemical Identifier
  11. ↑ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  12. ↑ DrugBank, Lengua ngrese, 17 Nuv 2015, 00542, Benazepril
  13. ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 19 Nuv 2016, Lengua ngrese, 6374, benazepril
  14. ↑ https://mednet-communities.net/inn/db/ViewINN.aspx?i=6129
  15. ↑ OpenAlex, 26 Jen 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  16. ↑ Freebase Data Dumps, 28 ott 2013
  17. ↑ ChemSpider, 19 Nuv 2016, Lengua ngrese, 4514935, Benazepril
  18. ↑ UniChem
  19. ↑ Hazardous Substances Data Bank, 10 Maj 2021, 28 ott 2019, Benazepril, 7081
  20. ↑ PubChem, 3 ott 2016, Lengua ngrese, 5362124, benazepril
  21. ↑ 21,0 21,1 inferred from InChI
  22. ↑ https://www.whocc.no/atc_ddd_index/?code=C09AA07
  23. ↑ RxNorm, 218088, 14 Fre 2018
  24. ↑ Recommended INN: List 28, 1988
  25. ↑ 25,0 25,1 N0000148336, 13 dic 2016, Lengua ngrese, NDF-RT
  26. ↑ Drug Indications Extracted from FAERS, 2 ott 2018
  27. ↑ LiverTox, 8 Abb 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/Benazepril, 1 set 2017
  28. ↑ N0000148336, 5 Màr 2018, NDF-RT
  29. ↑ 29,0 29,1 Medical Subject Headings, 15 Màr 2018, C044946
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